Select Research Publications:
Ortiz R, Joseph JJ, Lee R, Wand GS, Golden SH. Type 2 diabetes and cardiometabolic risk associated with increase in DNA methylation of FKBP5. Original research. Clinical Epigenetics. 2018. 10:82.
Ortiz R and Sibinga EM. The role of mindfulness in reducing the adverse effects of childhood stress and trauma. Children. 2017. 4(3),16; doi:10.3390/children4030016
Ortiz R, Chandros Hull S, Colloca L. Patient attitudes about the clinical use of placebo: qualitative perspectives from a telephone survey. BMJ Open. 2016: Apr 4;6(4):e011012.
Ortiz R, Ballard ED, Machado-Vieira R, Saligan LN, Walitt B. Quantifying the influence of child abuse history on the cardinal symptoms of fibromyalgia. Clin Exp Rheumatol. 2016 Mar-Apr;34(2 Suppl 96):S59-66. Epub 2016 Jan 8.
Stratton P, Khachikyan I, Sinaii N, Ortiz R, Shah J. Association of chronic pelvic pain and endometriosis with signs of sensitization and myofascial pain. Obstet Gynecol. 2015 Mar;125(3):719-28. doi: 10.1097/AOG.0000000000000663.
Ortiz R, Ulrich H, Zarate CA, Machado-Vieira R. Purinergic system dysfunction in mood disorders: a key target for development of improved therapeutics. Review. Prog Neuropsychopharmacol Biol Psychiatry. 2015 Mar 3;57:117-31. doi: 10.1016/j.pnpbp.2014.10.016. Epub 2014 Nov 7.
Ortiz R, Lukkahati N, Saligan LN, Nugent AC, Niciu MJ, Luckenbaugh DA, Machado-Vieira R, Zarate CA. Shank3 as a potential biomarker of antidepressant response to ketamine and its neural correlates in bipolar depression. J Affective Disorders. 2015 Feb 1;172:307-11. doi: 10.1016/j.jad.2014.09.015. Epub 2014 Oct 16.
Simmons K*, Ortiz R*, Kosswsky J, Krummenacher P, Grillon C, Miller FG, Pine D, Colloca L. Pain and Placebo in Pediatrics: A comprehensive review of laboratory and clinical findings. Review. *These authors contributed equally. Pain. 2014 Nov;155(11):2229-35. doi: 10.1016/j.pain.2014.08.036. Epub 2014 Aug 29.
Migliore MM, Ortiz R, Dye S, Campbell RB, Amiji MM, Waszczak BL. Neurotrophic and neuroprotective efficacy of intranasal GDNF in a rat model of Parkinson’s disease. Neuroscience 2014 Aug 22;274:11-23. doi: 10.1016/j.neuroscience.2014.05.019. Epub 2014 May 17.
Sikdar S, Ortiz R, Gebreab T, Gerber LH, and Shah JP. Understanding the vascular environment of myofascial trigger points using ultrasonic imaging and computational modeling. Conf Proc IEEE Eng Med Biol Soc. 2010.
Migliore MM, Ortiz R, Dye S, Gray S, Campbell RB, Amiji MM, Waszczak BL. Intranasal GDNF exerts a neurotrophic effect on midbrain dopamine neurons in the rat. American Journal of Pharmaceutical Education, 73 (4) Article 57. 2009.